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Sequence Detail
ID/Version
P54761 Q99MR2 Q60627 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Ephrin type-B receptor 4; EC=2.7.10.1;AltName: Full=Developmental kinase 2; Short=mDK-2;AltName: Full=Hepatoma transmembrane kinase;AltName: Full=Tyrosine kinase MYK-1;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 987 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ephb4 Eph receptor B4 31 127 4 11
Sequence references in MGI J:17851 Andres AC, et al., Expression of two novel eph-related receptor protein tyrosine kinases in mammary gland development and carcinogenesis [published erratum appears in Oncogene 1994 Aug;9(8):2431]. Oncogene. 1994 May;9(5):1461-7
J:29979 Ciossek T, et al., Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family. Oncogene. 1995 Nov 16;11(10):2085-95
J:57908 Gerety SS, et al., Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell. 1999 Sep;4(3):403-14
J:67990 Wilson MD, et al., Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5. Nucleic Acids Res. 2001 Mar 15;29(6):1352-65
J:237127 Martin-Almedina S, et al., EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis. J Clin Invest. 2016 Aug 01;126(8):3080-8
J:241039 Alonso-Martin S, et al., Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis. Front Cell Dev Biol. 2016;4:58
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory