Sequence Detail

ID/Version

P50431 Q64508 Q8R0X9 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Serine hydroxymethyltransferase, cytosolic {ECO:0000305|PubMed:11063567}; Short=SHMT {ECO:0000303|PubMed:11063567}; Short=cSHMT {ECO:0000303|PubMed:11063567}; EC=2.1.2.1 {ECO:0000250|UniProtKB:P34896};AltName: Full=Gl

Provider

SWISS-PROT

Sequence

Polypeptide 478 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Shmt1	serine hydroxymethyltransferase 1 (soluble)	87	103	3	46

Sequence references in MGI

J:36385 Nakshatri H, et al., Isolation of retinoic acid-repressed genes from P19 embryonal carcinoma cells. Gene. 1996 Sep 26;174(1):79-84
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:376490 Szebenyi DM, et al., Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: evidence for asymmetric obligate dimers. Biochemistry. 2000 Nov 7;39(44):13313-23