Sequence Detail

ID/Version

P50171 Q9Z1W2 Q5M9K0 Q60958 Q60959 (UniProt | EBI)

Last sequence update: 2010-04-20
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=(3R)-3-hydroxyacyl-CoA dehydrogenase; EC=1.1.1.n12 {ECO:0000250|UniProtKB:Q92506};AltName: Full=17-beta-hydroxysteroid dehydrogenase 8; Short=17-beta-HSD 8;AltName: Full=3-ketoacyl-[acyl-carrier-protein] reductase alpha subun

Provider

SWISS-PROT

Sequence

Polypeptide 259 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hsd17b8	hydroxysteroid 17-beta dehydrogenase 8	28	98	3	6

Sequence references in MGI

J:4344 Aziz N, et al., Downregulation of Ke 6, a novel gene encoded within the major histocompatibility complex, in murine polycystic kidney disease [published erratum appears in Mol Cell Biol 1993 Oct;13(10):6614]. Mol Cell Biol. 1993 Mar;13(3):1847-53
J:29463 Maxwell MM, et al., Ke 6 gene. Sequence and organization and aberrant regulation in murine polycystic kidney disease. J Biol Chem. 1995 Oct 20;270(42):25213-9
J:94120 Fomitcheva J, et al., Characterization of Ke 6, a new 17beta-hydroxysteroid dehydrogenase, and its expression in gonadal tissues. J Biol Chem. 1998 Aug 28;273(35):22664-71
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89