ID/Version |
|
||||||||||||||
Sequence description from provider |
RecName: Full=Neuronal acetylcholine receptor subunit alpha-7; Short=nAChR7;AltName: Full=Nicotinic acetylcholine receptor subunit alpha-7;Flags: Precursor; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
502
aa
|
||||||||||||||
Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
|
||||||||||||||
Sequence references in MGI |
J:24219
Orr-Urtreger A, et al., Cloning and mapping of the mouse alpha 7-neuronal nicotinic acetylcholine receptor. Genomics. 1995 Mar 20;26(2):399-402
J:89610 Wang H, et al., Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature. 2003 Jan 23;421(6921):384-8 J:100458 de Jonge WJ, et al., Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. Nat Immunol. 2005 Aug;6(8):844-51 J:300750 George AA, et al., Implications of Oligomeric Amyloid-Beta (oAbeta42) Signaling through alpha7beta2-Nicotinic Acetylcholine Receptors (nAChRs) on Basal Forebrain Cholinergic Neuronal Intrinsic Excitability and Cognitive Decline. J Neurosci. 2021 Jan 20;41(3):555-575 J:304156 Kweon HJ, et al., NACHO Engages N-Glycosylation ER Chaperone Pathways for alpha7 Nicotinic Receptor Assembly. Cell Rep. 2020 Aug 11;32(6):108025 J:359380 Tsoyi K, et al., Stimulation of alpha7 nicotinic acetylcholine receptor by nicotine attenuates inflammatory response in macrophages and improves survival in experimental model of sepsis through heme oxygenase-1 induction. Antioxid Redox Signal. 2011 Jun;14(11):2057-70 J:359791 Kim TH, et al., Stimulation of the alpha7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation. J Infect Dis. 2014 May 15;209(10):1668-77 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 03/18/2025 MGI 6.24 |
![]() |
|