Sequence Detail

ID/Version

P49183 O70532 (UniProt | EBI)

Last sequence update: 1999-07-15
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Deoxyribonuclease-1; EC=3.1.21.1 {ECO:0000250|UniProtKB:P24855};AltName: Full=Deoxyribonuclease I; Short=DNase I;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 284 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dnase1	deoxyribonuclease I	16	98	3	12

Sequence references in MGI

J:22846 Peitsch MC, et al., Genomic organisation and expression of mouse deoxyribonuclease I. Biochem Biophys Res Commun. 1995 Feb 6;207(1):62-8
J:41312 Takeshita H, et al., Mouse deoxyribonuclease I (DNase I): biochemical and immunological characterization, cDNA structure and tissue distribution. Biochem Mol Biol Int. 1997 Jun;42(1):65-75
J:62549 Napirei M, et al., Features of systemic lupus erythematosus in Dnase1-deficient mice [see comments]. Nat Genet. 2000 Jun;25(2):177-81
J:113757 Napirei M, et al., Expression pattern of the deoxyribonuclease 1 gene: lessons from the Dnase1 knockout mouse. Biochem J. 2004 Jun 15;380(Pt 3):929-37
J:252490 Jimenez-Alcazar M, et al., Host DNases prevent vascular occlusion by neutrophil extracellular traps. Science. 2017 Dec 1;358(6367):1202-1206
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89