Sequence Detail

ID/Version

P43680 Q3UND6 Q9EQ73 (UniProt | EBI)

Last sequence update: 2002-10-10
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Transcription factor SOX-18;

Provider

SWISS-PROT

Sequence

Polypeptide 377 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sox18	SRY (sex determining region Y)-box 18	58	115	3	11

Sequence references in MGI

J:28005 Hosking BM, et al., Trans-activation and DNA-binding properties of the transcription factor, Sox-18. Nucleic Acids Res. 1995 Jul 25;23(14):2626-8
J:28369 Dunn TL, et al., Sequence and expression of Sox-18 encoding a new HMG-box transcription factor. Gene. 1995 Aug 19;161(2):223-5
J:61488 Pennisi D, et al., Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice. Nat Genet. 2000 Apr;24(4):434-7
J:66010 Pennisi D, et al., Mice null for sox18 are viable and display a mild coat defect. Mol Cell Biol. 2000 Dec;20(24):9331-6
J:66073 Pennisi DJ, et al., Structure, mapping, and expression of human SOX18. Mamm Genome. 2000 Dec;11(12):1147-9
J:83731 James K, et al., Sox18 mutations in the ragged mouse alleles ragged-like and opossum. Genesis. 2003 May;36(1):1-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113127 Matsui T, et al., Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice. J Cell Sci. 2006 Sep 1;119(Pt 17):3513-26
J:143564 Francois M, et al., Sox18 induces development of the lymphatic vasculature in mice. Nature. 2008 Dec 4;456(7222):643-7
J:150211 Downes M, et al., Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation. Hum Mol Genet. 2009 Aug 1;18(15):2839-50
J:175110 Hosking BM, et al., SOX18 directly interacts with MEF2C in endothelial cells. Biochem Biophys Res Commun. 2001 Sep 21;287(2):493-500