Sequence Detail

ID/Version

P43142 G3X9R9 (UniProt | EBI)

Last sequence update: 2026-01-28
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Atypical chemokine receptor 5;AltName: Full=G-protein coupled receptor 182;AltName: Full=G10D;AltName: Full=NOW;

Provider

SWISS-PROT

Sequence

Polypeptide 398 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gpr182	G protein-coupled receptor 182	10	102	3	7

Sequence references in MGI

J:15563 Wilkie TM, et al., Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors. Genomics. 1993 Nov;18(2):175-84
J:305796 Le Mercier A, et al., GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2021596118
J:320174 Torphy RJ, et al., GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models. Nat Commun. 2022 Jan 10;13(1):97
J:338927 Melgrati S, et al., GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity. Front Immunol. 2023;14:1242531
J:343239 Bonnavion R, et al., Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5). Front Pharmacol. 2023;14:1297596