Sequence Detail

ID/Version

P42859 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Huntingtin;AltName: Full=Huntington disease protein homolog; Short=HD protein homolog;Contains: RecName: Full=Huntingtin, myristoylated N-terminal fragment {ECO:0000250|UniProtKB:P42858};

Provider

SWISS-PROT

Sequence

Polypeptide 3119 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Htt	huntingtin	198	111	3	114

Sequence references in MGI

J:16635 Lin B, et al., Sequence of the murine Huntington disease gene: evidence for conservation, and polymorphism in a triplet (CCG) repeat alternate slicing. Hum Mol Genet. 1994 Jan;3(1):85-92
J:18404 Barnes GT, et al., Mouse Huntington's disease gene homolog (Hdh). Somat Cell Mol Genet. 1994 Mar;20(2):87-97
J:23247 Lin B, et al., Structural analysis of the 5' region of mouse and human Huntington disease genes reveals conservation of putative promoter region and di- and trinucleotide polymorphisms. Genomics. 1995 Feb 10;25(3):707-15
J:24940 Trottier Y, et al., Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form [see comments]. Nat Genet. 1995 May;10(1):104-10
J:81675 Modregger J, et al., Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. J Biol Chem. 2003 Feb 7;278(6):4160-7
J:233660 Lemonidis K, et al., Identification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13 S-Acyltransferases. J Biol Chem. 2015 Sep 4;290(36):21939-50
J:277863 Peters MF, et al., Isolation of a 40-kDa Huntingtin-associated protein. J Biol Chem. 2001 Feb 2;276(5):3188-94
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89