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Sequence Detail
ID/Version
P35230 (UniProt | EBI) Last sequence update: 1994-02-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Regenerating islet-derived protein 3-beta {ECO:0000305}; Short=REG-3-beta;AltName: Full=Pancreatitis-associated protein 1;AltName: Full=Regenerating islet-derived protein III-beta; Short=Reg III-beta;Contains: RecName: Full=
Provider SWISS-PROT
Sequence
Polypeptide 175 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Reg3b regenerating islet-derived 3 beta 28 102 3 12
Sequence references in MGI J:4201 Itoh T, et al., Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP). Biochim Biophys Acta. 1993 Feb 20;1172(1-2):184-6
J:38547 Narushima Y, et al., Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma. Gene. 1997 Feb 7;185(2):159-68
J:182550 van Ampting MT, et al., Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice. Infect Immun. 2012 Mar;80(3):1115-20
J:196632 Stelter C, et al., Salmonella-induced mucosal lectin RegIIIbeta kills competing gut microbiota. PLoS One. 2011;6(6):e20749
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306415 Zhang H, et al., REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway. Commun Biol. 2021 Jun 7;4(1):688

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory