Sequence Detail

ID/Version

P33766 Q3UV01 (UniProt | EBI)

Last sequence update: 1994-02-01
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=N-formyl peptide receptor 1;AltName: Full=N-formylpeptide chemoattractant receptor;AltName: Full=fMet-Leu-Phe receptor; Short=fMLP receptor;

Provider

SWISS-PROT

Sequence

Polypeptide 364 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fpr1	formyl peptide receptor 1	38	97	6	8

Sequence references in MGI

J:43394 Gao JL, et al., Species and subtype variants of the N-formyl peptide chemotactic receptor reveal multiple important functional domains. J Biol Chem. 1993 Dec 5;268(34):25395-401
J:53354 Gao JL, et al., Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor. J Exp Med. 1999 Feb 15;189(4):657-62
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:137613 Southgate EL, et al., Identification of formyl peptides from Listeria monocytogenes and Staphylococcus aureus as potent chemoattractants for mouse neutrophils. J Immunol. 2008 Jul 15;181(2):1429-37
J:150065 Liberles SD, et al., Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9842-7
J:164871 McDonald B, et al., Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science. 2010 Oct 15;330(6002):362-6
J:227052 Vacchelli E, et al., Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1. Science. 2015 Nov 20;350(6263):972-8
J:283337 Osei-Owusu P, et al., FPR1 is the plague receptor on host immune cells. Nature. 2019 Oct;574(7776):57-62