Sequence Detail

ID/Version

P30557 (UniProt | EBI)

Last sequence update: 1993-04-01
Last annotation update: 2023-11-08

Sequence description from provider

RecName: Full=Prostaglandin E2 receptor EP3 subtype; Short=PGE receptor EP3 subtype; Short=PGE2 receptor EP3 subtype;AltName: Full=Prostanoid EP3 receptor;

Provider

SWISS-PROT

Sequence

Polypeptide 365 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ptger3	prostaglandin E receptor 3 (subtype EP3)	57	104	3	10

Sequence references in MGI

J:150 Sugimoto Y, et al., Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype. J Biol Chem. 1992 Apr 5;267(10):6463-6
J:15691 Irie A, et al., Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase. Eur J Biochem. 1993 Oct 1;217(1):313-8
J:15973 Sugimoto Y, et al., Two isoforms of the EP3 receptor with different carboxyl-terminal domains. Identical ligand binding properties and different coupling properties with Gi proteins. J Biol Chem. 1993 Feb 5;268(4):2712-8
J:52323 Fleming EF, et al., Urinary concentrating function in mice lacking EP3 receptors for prostaglandin E2. Am J Physiol. 1998 Dec;275(6 Pt 2):F955-61
J:59696 Takeuchi K, et al., Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP(3). Gastroenterology. 1999 Nov;117(5):1128-35
J:70534 Ushikubi F, et al., Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3. Nature. 1998 Sep 17;395(6699):281-4
J:103136 Ma H, et al., Increased bleeding tendency and decreased susceptibility to thromboembolism in mice lacking the prostaglandin E receptor subtype EP(3). Circulation. 2001 Sep 4;104(10):1176-80