Sequence Detail

ID/Version

P17532 (UniProt | EBI)

Last sequence update: 1990-08-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Tryptophan 5-hydroxylase 1 {ECO:0000305}; EC=1.14.16.4 {ECO:0000305|PubMed:2110547};AltName: Full=Tryptophan 5-monooxygenase 1;

Provider

SWISS-PROT

Sequence

Polypeptide 447 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tph1	tryptophan hydroxylase 1	29	119	4	20

Sequence references in MGI

J:10480 Stoll J, et al., Characterization and chromosomal mapping of a cDNA encoding tryptophan hydroxylase from a mouse mastocytoma cell line. Genomics. 1990 May;7(1):88-96
J:87273 Walther DJ, et al., Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. Cell. 2003 Dec 26;115(7):851-62