Sequence Detail

ID/Version

P16382 O54690 Q60583 Q8CBW5 (UniProt | EBI)

Last sequence update: 1990-08-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Interleukin-4 receptor subunit alpha; Short=IL-4 receptor subunit alpha; Short=IL-4R subunit alpha; Short=IL-4R-alpha; Short=IL-4RA;AltName: CD_antigen=CD124;Contains: RecName: Full=Soluble interleukin-4 rece

Provider

SWISS-PROT

Sequence

Polypeptide 810 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Il4ra	interleukin 4 receptor, alpha	29	105	3	24

Sequence references in MGI

J:4046 Wrighton N, et al., The murine interleukin-4 receptor gene: genomic structure, expression and potential for alternative splicing. Growth Factors. 1992;6(2):103-18
J:10282 Harada N, et al., Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding. Proc Natl Acad Sci U S A. 1990 Feb;87(3):857-61
J:32360 Mosley B, et al., The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms. Cell. 1989 Oct 20;59(2):335-48
J:34898 Blum H, et al., Two distinct stimulus-dependent pathways lead to production of soluble murine interleukin-4 receptor. J Immunol. 1996 Sep 1;157(5):1846-53
J:43798 Schulte T, et al., Molecular characterization and functional analysis of murine interleukin 4 receptor allotypes. J Exp Med. 1997 Nov 3;186(9):1419-29
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113957 Seki Y, et al., Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13003-8
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:223721 Moshkovits I, et al., CD300f associates with IL-4 receptor alpha and amplifies IL-4-induced immune cell responses. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8708-13