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Sequence Detail
ID/Version
P15920 Q8VHU0 A4FU82 Q9JHJ2 Q3U2X3 (UniProt | EBI) Last sequence update: 2001-01-11
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=V-type proton ATPase 116 kDa subunit a 2; Short=V-ATPase 116 kDa subunit a 2;AltName: Full=Immune suppressor factor J6B7; Short=ISF;AltName: Full=Lysosomal H(+)-transporting ATPase V0 subunit a 2;AltName: Full=ShIF;AltName: F
Provider SWISS-PROT
Sequence
Polypeptide 856 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Atp6v0a2 ATPase, H+ transporting, lysosomal V0 subunit A2 23 112 3 4
Sequence references in MGI J:30662 Lee C, et al., Cloning of a cDNA for a T cell produced molecule with a putative immune regulatory role. Mol Immunol. 1990 Nov;27(11):1137-44
J:61083 Nishi T, et al., Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase. J Biol Chem. 2000 Mar 10;275(10):6824-30
J:61380 Toyomura T, et al., Three subunit a isoforms of mouse vacuolar H(+)-ATPase. Preferential expression of the a3 isoform during osteoclast differentiation. J Biol Chem. 2000 Mar 24;275(12):8760-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116421 Hurtado-Lorenzo A, et al., V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nat Cell Biol. 2006 Feb;8(2):124-36
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory