Sequence Detail

ID/Version

P11247 Q5NCP1 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Myeloperoxidase {ECO:0000303|PubMed:2548170}; Short=MPO {ECO:0000303|PubMed:2548170}; EC=1.11.2.2 {ECO:0000269|PubMed:11593004, ECO:0000269|PubMed:23306200};Contains: RecName: Full=Myeloperoxidase light chain;Contains: RecN

Provider

SWISS-PROT

Sequence

Polypeptide 718 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mpo	myeloperoxidase	85	111	4	14

Sequence references in MGI

J:9933 Venturelli D, et al., Nucleotide sequence of cDNA for murine myeloperoxidase. Nucleic Acids Res. 1989 Jul 25;17(14):5852
J:10065 Venturelli D, et al., Sequence of the murine myeloperoxidase (MPO) gene. Nucleic Acids Res. 1989 Oct 11;17(19):7987-8
J:53993 Aratani Y, et al., Severe impairment in early host defense against Candida albicans in mice deficient in myeloperoxidase. Infect Immun. 1999 Apr;67(4):1828-36
J:126649 Gaut JP, et al., Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis. Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):11961-6
J:196714 Chapman AL, et al., Ceruloplasmin is an endogenous inhibitor of myeloperoxidase. J Biol Chem. 2013 Mar 1;288(9):6465-77
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:329686 Mathew AV, et al., Deletion of bone marrow myeloperoxidase attenuates chronic kidney disease accelerated atherosclerosis. J Biol Chem. 2021 Jan-Jun;296:100120