Sequence Detail

ID/Version

P11088 (UniProt | EBI)

Last sequence update: 1989-07-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Filaggrin;Flags: Fragment;

Provider

SWISS-PROT

Sequence

Polypeptide 336 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Flg	filaggrin	7	158	0	7

Sequence references in MGI

J:6708 Holbrook KA, et al., Abnormal epidermal keratinization in the repeated epilation mutant mouse. J Cell Biol. 1982 Feb;92(2):387-97
J:22334 Rothnagel JA, et al., The gene for mouse epidermal filaggrin precursor. Its partial characterization, expression, and sequence of a repeating filaggrin unit. J Biol Chem. 1987 Nov 15;262(32):15643-8
J:214772 Fischer H, et al., Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation. J Invest Dermatol. 2014 Oct;134(10):2579-88
J:215250 Madsen DH, et al., TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition. Biochem J. 2014 Aug 1;461(3):487-95