Sequence Detail

ID/Version

P11087 Q61427 Q810J9 Q63919 Q6PCL3 Q61367 Q53WT0 Q60635 (UniProt | EBI)

Last sequence update: 2005-12-06
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Collagen alpha-1(I) chain {ECO:0000305};AltName: Full=Alpha-1 type I collagen;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1453 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Col1a1	collagen, type I, alpha 1	97	241	4	228

Sequence references in MGI

J:7398 Harbers K, et al., Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice. Proc Natl Acad Sci U S A. 1984 Mar;81(5):1504-8
J:11264 Metsaranta M, et al., Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs. Biochim Biophys Acta. 1991 Jun 13;1089(2):241-3
J:16227 Fenton SP, et al., Genomic sequence of mouse COL1A1 encoding the collagen propeptides. Biochim Biophys Acta. 1993 Dec 14;1216(3):469-74
J:28627 Li SW, et al., The complete cDNA coding sequence for the mouse pro alpha 1(I) chain of type I procollagen. Matrix Biol. 1995 Jul;14(7):593-5
J:31518 Rhodes K, et al., DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism. Mol Cell Biol. 1994 Sep;14(9):5950-60
J:32372 Monson JM, et al., DNA sequence analysis of a mouse pro alpha 1 (I) procollagen gene: evidence for a mouse B1 element within the gene. Mol Cell Biol. 1982 Nov;2(11):1362-71
J:43427 Mooslehner K, et al., Two mRNAs of mouse pro alpha 1(I) collagen gene differ in the size of the 3'-untranslated region. Nucleic Acids Res. 1988 Jan 25;16(2):773
J:48575 French BT, et al., Nucleotide sequence of a cDNA clone for mouse pro alpha 1(I) collagen protein. Gene. 1985;39(2-3):311-2
J:220554 Hudson DM, et al., Post-translationally Abnormal Collagens of Prolyl 3-Hydroxylase-2 Null Mice Offer a Pathobiological Mechanism for the High Myopia Linked to Human LEPREL1 Mutations. J Biol Chem. 2015 Mar 27;290(13):8613-22
J:232567 Heard ME, et al., Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation. PLoS Genet. 2016 Apr;12(4):e1006002
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:341423 Feng XY, et al., Homeobox protein MSX-1 inhibits expression of bone morphogenetic protein 2, bone morphogenetic protein 4, and lymphoid enhancer-binding factor 1 via Wnt/beta-catenin signaling to prevent differentiation of dental mesenchymal cells during the late bell stage. Eur J Oral Sci. 2018 Feb;126(1):1-12
J:341424 Feng XY, et al., Msx1 regulates proliferation and differentiation of mouse dental mesenchymal cells in culture. Eur J Oral Sci. 2013 Oct;121(5):412-20