Sequence Detail

ID/Version

P10856 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Spermatid nuclear transition protein 1; Short=STP-1; Short=TP-1;

Provider

SWISS-PROT

Sequence

Polypeptide 55 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tnp1	transition protein 1	35	100	2	6

Sequence references in MGI

J:9223 Kleene KC, et al., Nucleotide sequence of a cDNA clone encoding mouse transition protein 1. Biochim Biophys Acta. 1988 Jul 13;950(2):215-20
J:11585 Yelick PC, et al., The mouse transition protein 1 gene contains a B1 repetitive element and is located on chromosome 1. Genomics. 1991 Nov;11(3):687-94
J:61941 Yu YE, et al., Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4683-8
J:89779 Zhao M, et al., Transition nuclear proteins are required for normal chromatin condensation and functional sperm development. Genesis. 2004 Apr;38(4):200-13
J:93181 Shirley CR, et al., Abnormalities and reduced reproductive potential of sperm from Tnp1- and Tnp2-null double mutant mice. Biol Reprod. 2004 Oct;71(4):1220-9
J:107120 Zhao M, et al., Nucleoprotein transitions during spermiogenesis in mice with transition nuclear protein Tnp1 and Tnp2 mutations. Biol Reprod. 2004 Sep;71(3):1016-25
J:241000 Barral S, et al., Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells. Mol Cell. 2017 Apr 06;66(1):89-101.e8