Sequence Detail

ID/Version

O54926 Q9CWL1 Q9R1Q0 Q9R1Q1 Q921I8 Q3U6J2 (UniProt | EBI)

Last sequence update: 1998-06-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Apoptosis regulatory protein Siva;AltName: Full=CD27-binding protein; Short=CD27BP;

Provider

SWISS-PROT

Sequence

Polypeptide 175 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Siva1	SIVA1, apoptosis-inducing factor	28	99	3	16

Sequence references in MGI

J:58916 Yoon Y, et al., Murine Siva-1 and Siva-2, alternate splice forms of the mouse Siva gene, both bind to CD27 but differentially transduce apoptosis. Oncogene. 1999 Nov 25;18(50):7174-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117429 Spinicelli S, et al., GITR interacts with the pro-apoptotic protein Siva and induces apoptosis. Cell Death Differ. 2002 Dec;9(12):1382-4
J:117434 Prasad KV, et al., CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6346-51