Sequence Detail

ID/Version

O54918 O54919 O54920 A2ALQ6 (UniProt | EBI)

Last sequence update: 1998-06-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Bcl-2-like protein 11; Short=Bcl2-L-11;AltName: Full=Bcl2-interacting mediator of cell death;

Provider

SWISS-PROT

Sequence

Polypeptide 196 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bcl2l11	BCL2 like 11	99	107	3	40

Sequence references in MGI

J:45671 O'Connor L, et al., Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 1998 Jan 15;17(2):384-95
J:85832 Liu X, et al., The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. Immunity. 2003 Sep;19(3):341-52
J:107746 Nitta T, et al., IAN family critically regulates survival and development of T lymphocytes. PLoS Biol. 2006 Apr;4(4):e103
J:167725 Galehdar Z, et al., Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J Neurosci. 2010 Dec 15;30(50):16938-48
J:177231 Thompson S, et al., Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. J Biol Chem. 2011 Jun 3;286(22):19331-9
J:201566 Maurer U, et al., Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell. 2006 Mar 17;21(6):749-60
J:235307 Weber A, et al., The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis. EMBO Rep. 2016 May;17(5):724-38
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89