Sequence Detail

ID/Version

O35855 Q8VD03 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Branched-chain-amino-acid aminotransferase, mitochondrial; Short=BCAT(m); EC=2.6.1.42 {ECO:0000269|PubMed:14755340};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 393 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bcat2	branched chain aminotransferase 2, mitochondrial	52	100	3	175

Sequence references in MGI

J:40040 Bledsoe RK, et al., Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm). Biochim Biophys Acta. 1997 Apr 25;1339(1):9-13
J:87589 Wu JY, et al., ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. J Clin Invest. 2004 Feb;113(3):434-40
J:129967 She P, et al., Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle. Cell Metab. 2007 Sep;6(3):181-94
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:369121 Ma QX, et al., BCAA-BCKA axis regulates WAT browning through acetylation of PRDM16. Nat Metab. 2022 Jan;4(1):106-122