Sequence Detail

ID/Version

O35205 (UniProt | EBI)

Last sequence update: 1998-01-01
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Granzyme K; EC=3.4.21.- {ECO:0000250|UniProtKB:P49863};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 263 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gzmk	granzyme K	38	104	3	10

Sequence references in MGI

J:49361 Shresta S, et al., Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes. J Biol Chem. 1997 Aug 8;272(32):20236-44
J:302067 Joeckel LT, et al., Granzyme K-deficient mice show no evidence of impaired antiviral immunity. Immunol Cell Biol. 2017 Sep;95(8):676-683
J:362530 Lan F, et al., GZMK-expressing CD8(+) T cells promote recurrent airway inflammatory diseases. Nature. 2025 Feb;638(8050):490-498
J:367062 Donado CA, et al., Granzyme K activates the entire complement cascade. Nature. 2025 May;641(8061):211-221