Sequence Detail

ID/Version

O08859 (UniProt | EBI)

Last sequence update: 1997-07-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Tumor necrosis factor-inducible gene 6 protein;AltName: Full=TNF-stimulated gene 6 protein; Short=TSG-6;AltName: Full=Tumor necrosis factor alpha-induced protein 6; Short=TNF alpha-induced protein 6;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 275 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tnfaip6	tumor necrosis factor alpha induced protein 6	31	96	3	7

Sequence references in MGI

J:44617 Fulop C, et al., Coding sequence, exon-intron structure and chromosomal localization of murine TNF-stimulated gene 6 that is specifically expressed by expanding cumulus cell-oocyte complexes. Gene. 1997 Nov 20;202(1-2):95-102
J:82539 Fulop C, et al., Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice. Development. 2003 May;130(10):2253-61
J:141906 Mahoney DJ, et al., TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation. J Biol Chem. 2008 Sep 19;283(38):25952-62