Sequence Detail

ID/Version

E9PYH6 (UniProt | EBI)

Last sequence update: 2011-04-05
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Histone-lysine N-methyltransferase SETD1A; EC=2.1.1.364 {ECO:0000305|PubMed:24550110};AltName: Full=SET domain-containing protein 1A;

Provider

SWISS-PROT

Sequence

Polypeptide 1716 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Setd1a	SET domain containing 1A	40	104	3	14

Sequence references in MGI

J:208420 Bledau AS, et al., The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation. Development. 2014 Mar;141(5):1022-35
J:263406 Qiao H, et al., Nap1l1 Controls Embryonic Neural Progenitor Cell Proliferation and Differentiation in the Developing Brain. Cell Rep. 2018 Feb 27;22(9):2279-2293
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:296132 Yu X, et al., De Novo and Inherited SETD1A Variants in Early-onset Epilepsy. Neurosci Bull. 2019 Dec;35(6):1045-1057