Sequence Detail

ID/Version

A4UUI3 A0A0G2JDT5 Q61594 B9EJ74 A0A0G2JEJ5 A0A0G2JGT4 (UniProt | EBI)

Last sequence update: 2007-05-15
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Guanylate-binding protein 4; EC=3.6.5.- {ECO:0000250|UniProtKB:P32455};AltName: Full=GTP-binding protein 4; Short=GBP-4;AltName: Full=Guanine nucleotide-binding protein 4;

Provider

SWISS-PROT

Sequence

Polypeptide 631 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gbp4	guanylate binding protein 4	19	96	6	5

Sequence references in MGI

J:2344 Wynn TA, et al., Identification and characterization of a new gene family induced during macrophage activation. J Immunol. 1991 Dec 15;147(12):4384-92
J:155210 Degrandi D, et al., Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense. J Immunol. 2007 Dec 1;179(11):7729-40
J:180378 Hu Y, et al., Guanylate binding protein 4 negatively regulates virus-induced type I IFN and antiviral response by targeting IFN regulatory factor 7. J Immunol. 2011 Dec 15;187(12):6456-62