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Fcgr1em1.1(icre)Moli - Mouse-other
Recombinase Activity Detail
Allele Information
Allele:
Fcgr1em1.1(icre)Moli
Fc receptor, IgG, high affinity I; endonuclease-mediated mutation 1, Ming O Li 		Driver: Fcgr1
Type: Endonuclease-mediated (Recombinase, Reporter)
Synonym: Fcgr1-cre, Fcgr1em1.1(cre)Moli
Molecular description: The targeting construct inserted IRES, tdTomato, T2A self-cleaving peptide, iCre recombinase, and an FRT site-flanked PGK-NEO-BGHpA cassette downstream of the stop codon of the Fcgr1 gene by CRISPRCas9-mediated homologous recombination in mouse ES cells. Mice harboring the targeted allele were subsequently crossed with Rosa26FLPe mice to remove the neo cassette. However, analysis of the mice revealed that a neo sequence closely linked to (or elsewhere within) the Fcgr1-cre allele is present. It has not been determined if the retained neo is a full or partial sequence, nor is it known where it lies near/within the Fcgr1-cre allele.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Mouse-other Other recombinase alleles with activity in Mouse-other tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
07/22/2025
MGI 6.24 		The Jackson Laboratory