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Tp(X)1SoffTg(Myh11-icre/ERT2)1Soff - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tp(X)1SoffTg(Myh11-icre/ERT2)1Soff
transposition, Chr X, Offermanns 1; transgene insertion 1, Stefan Offermanns 		Driver: Myh11
Type: Spontaneous (Recombinase)
Synonym:
Molecular description: The mouse promoter from BAC clone 26630 was used to drive inducible icre expression in smooth muscle cells. An FRT-flanked beta-lactamase gene contained within the cre/ESR1 cassette was removed by flp mediated recombination. The transgene that originally integrated into Chr Y was found to to have translocated to Chr X in some female mice in the colony. The exact position is unknown.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:248193 Fig. 3 J:248193 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory