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Ankfn1tm2.1(cre)Mnw - Head
Recombinase Activity Detail
Allele Information
Allele:
Ankfn1tm2.1(cre)Mnw
ankyrin-repeat and fibronectin type III domain containing 1; targeted mutation 2.1, Mark N Wu 		Driver: Ankfn1
Type: Targeted (Null/knockout, Recombinase, Reporter)
Synonym: mWAKECre
Molecular description: Using homologous recombination in ES cells, the knock-in vector targeted exon 5 of the Ankfn1 locus and was integrated 21 bp into exon 5, replacing the remainder of the exon with a tdTomato-P2A-split Cre-Neo-WPREBGHpA cassette, which causes frameshifted nonsense mutations downstream, resulting in the loss-of-function allele. Neomycin was excised via FLP mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Ankfn1tm2.1(cre)Mnw activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory