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Tg(Krt18-EGFP,Krt8-cre/ERT)HCmch - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Krt18-EGFP,Krt8-cre/ERT)HCmch
transgene insertion H, Chun-Ming Chen 		Driver: Krt8
Type: Transgenic (Inducible, Recombinase, Reporter)
Inducer: tamoxifen
Synonym: K8-CEtg, Tg(K18-EGFP;K8-CreERT)
Molecular description: The mice promoters contained within a 24 kb intergenic region drive prostate luminal cell-specific expression of the EGFP reporter gene and tamoxifen-inducible cre recombinase gene (cre/ERT), respectively. The cre fusion is followed by a polyadenylation sequence and 2 copies of the chicken beta globin 5' HS4 insulator sequence. 24 kb of the intergenic region that separates the promoters. The pound symbol is used when no line is specified and/or liens are pooled.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Krt18-EGFP,Krt8-cre/ERT)HCmch activity also observed in:
reproductive system
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory