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Prg4tm1(GFP/cre/ERT2)Abl - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Prg4tm1(GFP/cre/ERT2)Abl
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein); targeted mutation 1, Andrew Lassar 		Driver: Prg4
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Prg4GFPCreERt2
Molecular description: A targeting vector containing a GFP/cre/ERT2 (green fluorescent protein, cre recombinase and estrogen receptor 1 tamoxifen binding domain fusion gene and an FRT flanked PGK-NEO selection cassette), was inserted into the translation initiation codon of exon 2 of the Prg4, proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein). The resulting chimeric animals were crossed to FLP recombinase expressing mice (ACT-FLPe) mice (on an unknown genetic background) to remove the Frt flanked PGK-neo selection cassette.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Images
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J:243210 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory