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Tg(Tpbpa-cre,-EGFP)5Jcc - Extraembryonic Component
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tpbpa-cre,-EGFP)5Jcc
transgene insertion 5, James C Cross 		Driver: Tpbpa
Type: Transgenic (Recombinase)
Synonym: Tpbpa-Cre, Tpbpa-Cre-GFP
Molecular description: Transgenic mice were generated using a construct in which a cre recombinase-IRES-EGFP cassette was cloned downstream of the Tpbpa promoter. Three independent lines were obtained and all lines produced similar temporal and spatial expression patterns of cre-EGFP that correlated with those of the endogenous Tpbpa gene. Line 5 was used for further studies as it showed earliest onset of expression (around E8.0). Activity of cre recombinase in reporter assays also was detected by E8.0.
Find mice (IMSR): Mouse Strains: 4 strains available       Cell Lines: 0 lines available
Tissue Information
Extraembryonic Component Other recombinase alleles with activity in Extraembryonic Component tissues:
Images
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J:122534 Fig. 7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 12 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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05/14/2024
MGI 6.23 		The Jackson Laboratory