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Slc32a1tm2(cre)Lowl - Head
Recombinase Activity Detail
Allele Information
Allele:
Slc32a1tm2(cre)Lowl
solute carrier family 32 (GABA vesicular transporter), member 1; targeted mutation 2, Bradford B Lowell 		Driver: Slc32a1
Type: Targeted (Recombinase)
Synonym: VGAT-Cre, vGATiresCre, Vgat-ires-Cre
Molecular description: A targeting vector, constructed from a BAC clone containing the Slc32a1 (Vgat) gene, was utilized to insert an internal ribosomal entry site followed by the cre recombinase sequence into the Slc32a1 locus just downstream of the endogenous stop codon. Cre is expressed from the Slc32a1 gene promoter. Immunohistochemistry on brain and Western blot analysis shows decreased expression of SLC32A1 protein in homozygotes.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Slc32a1tm2(cre)Lowl activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:331457 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 311 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory