Opn4<tm1.1(cre)Saha> - Head Recombinase Activity Detail MGI Mouse

Opn4^{tm1.1(cre)Saha} - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Opn4^{tm1.1(cre)Saha}
opsin 4 (melanopsin); targeted mutation 1.1, Samer Hattar

Driver: Opn4
Type: Targeted (Recombinase)

Synonym:

Opn4^Cre

Molecular description:

Cre recombinase preceded by a human beta-globin intron and nuclear localization signal was inserted immediately after the start codon of the Opn4 gene, replacing the open reading frame. An FRT-flanked pgk-neo cassette followed the cre coding sequence. Homologous recombination in ES cells resulted in replacement of the coding region of Opn4 with this construct. After establishing germline transmission of the allele, mice were crossed to Flp-expressing animals to remove the neo cassette with the Flp gene subsequently bred out of the line in creating homozygous mutants.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Opn4^{tm1.1(cre)Saha} activity also observed in:
nervous system, sensory organs

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

51 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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