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Gad1tm2(cre)Tama - Head
Recombinase Activity Detail
Allele Information
Allele:
Gad1tm2(cre)Tama
glutamate decarboxylase 1; targeted mutation 2, Nobuaki Tamamaki 		Driver: Gad1
Type: Targeted (Recombinase)
Synonym: Gad1tm1(cre)Tama, GAD67-Cre
Molecular description: A targeting vector was designed where the cre recombinase gene was inserted into immediately after the translational initiation site of the Gad1 (GAD67) gene in frame. This vector contained a 3-kb fragment at the 5' side, the cre gene inserted behind the Gad1 translational start, a Pgk-neo-p(A) cassette flanked by two Flp recognition target (FRT) sites, a 7-kb fragment at the 3' side, and an MC1 promoter-driven diphtheria toxin gene for selection. The vector was introduced into C57BL/6 ES cells and ES cells showing homologous recombination were injected into 8-cell stage CD-1 embryos. This allele is a null allele.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Gad1tm2(cre)Tama activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:173688 Fig. 6 J:173688 Fig. 8 J:173688 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory