Vamp2<tm1(cre/ERT)Nat> - Head Recombinase Activity Detail MGI Mouse

Vamp2^{tm1(cre/ERT)Nat} - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Vamp2^{tm1(cre/ERT)Nat}
vesicle-associated membrane protein 2; targeted mutation 1, Jeremy Nathans

Driver: Vamp2
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

VAMP2-IRES-creER, Vamp2^{tm1(cre/Esr1)Nat}

Molecular description:

An IRES-creER cassette, a tetracycline resistance gene and a Frt-flanked neomycin selection marker were all knocked in to the 3' UTR of the gene. The neomycin selection marker was removed by crossing to a C57BL/6 background Flp recombinase strain. Flp was then bred out of the line. When crossed with a Tg(CAG-Bgeo/ALPP)1Lbe reporter strain and given tamoxifen, cre expression was detected in a wide variety of neural and glial cells of the brain. This is line B4.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Vamp2^{tm1(cre/ERT)Nat} activity also observed in:
nervous system

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Images

Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images

J:144315 Fig. 2

Recombinase Activity

Click heading to re-sort table.

Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23