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Mapttm2(cre)Aha - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Mapttm2(cre)Aha
microtubule-associated protein tau; targeted mutation 2, Akihiro Harada 		Driver: Mapt
Type: Targeted (Recombinase)
Synonym: tau-Cre
Molecular description: A cre gene with a nuclear localization signal followed by an frt-flanked neo cassette was inserted immediately after the start methionine. Cre function is dectected in neurons of almost all areas of the brain with only granule cells in the caudal part of the cerebellum not exhbiting cre function. Other organs such as the liver, kidney and intestine do not exhibit cre function.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Mapttm2(cre)Aha activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory