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Tg(Neurog1-cre/ERT2)1Good - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Neurog1-cre/ERT2)1Good
transgene insertion 1, Lisa V Goodrich 		Driver: Neurog1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Neurog1CreER, Ngn1CreER, Ngn1-CreERT2, Ngn-CreERT2, Tg(Neurog1-cre/ESR1)1Good
Molecular description: A transgene was constructed where cre recombinase fused to the ligand-binding domain of a mutant human estrogen receptor was placed under the control of the upstream promoter and the downstream untranslated region of the Neurog1 gene. Cre activity was detected in cochlear ganglion neurons of transgenic mice when crossed with a cre-reporter strain and dosing with tamoxifen.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Neurog1-cre/ERT2)1Good activity also observed in:
head, sensory organs
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:130813 Fig. 1 J:130813 Fig. 2 J:130813 Fig. 3 J:130813 Fig. 4 J:130813 Fig. 5 J:130813 Fig. 6 J:130813 Fig. 7 J:130813 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 26 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory