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Tg(Nkx2-1-cre)1Wdr - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nkx2-1-cre)1Wdr
transgene insertion 1, William D Richardson 		Driver: Nkx2-1
Type: Transgenic (Recombinase)
Synonym: Nkx2.1Cre, Nkx2.1-Cre, Nkx2.1:Cre, Nkx2.1iCre
Molecular description: A P1 artificial chromosome was created that contained a condon-improved Cre recombinase with a nuclear localization signal fused to the initiation codon. Expression recapitulates endogenous expression in the medial ganglionic eminence, septum, anterior entopeduncular area, preoptic area and other more posterior ventral forebrain regions.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nkx2-1-cre)1Wdr activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:164291 Fig. 5 J:164291 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 31 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory