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Slc6a4tm1(cre)Xz - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Slc6a4tm1(cre)Xz
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; targeted mutation 1, Xiaoxi Zhuang 		Driver: Slc6a4
Type: Targeted (Recombinase)
Synonym: SERT-cre
Molecular description: A targeting vector was constructed by inserting a cassette with the cre recombinase coding sequence, a nuclear translocation signal, and a PGK-neo gene flanked by FRT sites, into the 5'-UTR of the Slc6a4 gene. After homologous recombination in ES cells, mice with cre recombinase expressed from the Slc6a4 locus were produced. Cre recombinase expression is detected in the Raphe nuclei. Flp-mediated recombination removed the FRT-flanked neo cassette.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Slc6a4tm1(cre)Xz activity also observed in:
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Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 67 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory