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Scn10atm3(cre/ERT2)Jwo - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Scn10atm3(cre/ERT2)Jwo
sodium channel, voltage-gated, type X, alpha; targeted mutation 3, John N Wood
Driver: Scn10a
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Nav1.8-CreERT2, Scn10atm3(cre/ERT2)Jnw
Molecular description: Cre recombinaseERT2 cDNA, 3' UTR of Scn10a, and an FRT flanked neo were knocked into the initiator methionine so that Cre replaced the ATG. Crossing with mice expressing Flp recombinase in the germ line excised the floxed neo.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:114488 Fig. 3 J:114488 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory