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Tg(AQP2-cre)2Dek - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(AQP2-cre)2Dek
transgene insertion 2, Donald E Kohan 		Driver: AQP2
Type: Transgenic (Recombinase)
Synonym:
Molecular description: This transgene consists of 14 kb from the 5'-flanking region of the human AQP2 driving expression of a modified cre recombinase that includes an SV40 nuclear localization signal and an 11 amino acid herpes simplex virus glycoprotein D epitope tag. Cre expression is seen in the collecting ducts of the kidney, the vas deferens, and the testis including post-meiotic sperm. Paternal inheritance of this transgene results in ubiquitous cre mediated recombination.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 28 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory