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Tg(Prrx1-cre)1Cjt - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Prrx1-cre)1Cjt
transgene insertion 1, Clifford J Tabin
Driver: Prrx1
Type: Transgenic (Recombinase)
Synonym: Prx1cre, Prx1-cre, Prx1Cre, Prx-1 Cre, Prx-cre, Tg[Prx1-cre]1Cjt
Molecular description: This transgene expresses Cre recombinase under the control of a Prrx1 derived enhancer. This transgene is expressed in the early limb bud mesenchyme and in a subset of craniofacial mesenchyme. A germline Cre recombinase activity was observed in female, but not in male, as partially penetrant trait depending on the particular gene flanked by loxP sites.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Prrx1-cre)1Cjt activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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Fig. Prrx1 Adult Cerebellum
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Fig. Prrx1 Adult Choroid Plexus
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Fig. Prrx1 Adult Cortex
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Fig. Prrx1 Adult Hippocampus
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Fig. Prrx1 Adult Medulla
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Fig. Prrx1 Adult Olfactory Bulb
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Fig. Prrx1 Adult Peripheral nerve
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Fig. Prrx1 Adult Thalamus
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Fig. Prrx1 E10.5 Diencephalon
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Fig. Prrx1 E10.5 Midbrain
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Fig. Prrx1 E15.5 Cranial nerve
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Fig. Prrx1 E15.5 Trigem ganglia
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 462 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory