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Tg(Tek-cre/ERT2)1Arnd - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tek-cre/ERT2)1Arnd
transgene insertion 1, Bernd Arnold
Driver: Tek
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: L43Tie2CreT2, Tg(Tek-cre/ESR1)1Arnd, Tie2-CreERT2, Tie2ERT2Cre
Molecular description: The transgenic construct encodes a tamoxifen-inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand-binding domain fused to the mouse Tek promoter and 10.5 kb of the first intron. Transgene expression in endothelial cells of the liver and kidney was confirmed by immunohistochemical analysis.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tek-cre/ERT2)1Arnd activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory