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Isl1tm1(cre)Tmj - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Isl1tm1(cre)Tmj
ISL1 transcription factor, LIM/homeodomain; targeted mutation 1, Thomas M Jessell
Driver: Isl1
Type: Targeted (Recombinase)
Synonym: Isl1cre, Isl1-Cre, Isl1-IRES-Cre, Isl1tm1(cre)Cos, Isl-Cre, Islet1:Cre
Molecular description: An IRES-Cre-SV40pA cassette was inserted into the exon encoding the second LIM domain of Isl1. Endogenous regulatory sequences drive Cre expression in motor neurons and dorsal root and cranial sensory ganglia.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Isl1tm1(cre)Tmj activity also observed in:
cardiovascular system, muscle
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:80963 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 77 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory