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H2az2Tg(Wnt1-cre)11Rth - Head
Recombinase Activity Detail
Allele Information
Allele:
H2az2Tg(Wnt1-cre)11Rth
H2A.Z histone variant 2; transgene insertion 11, David H Rowitch
Driver: Wnt1
Type: Transgenic (Recombinase)
Synonym: Tg(Wnt1-cre)11Rth, Wnt1cre, Wnt1Cre, Wnt1-Cre, Wnt1::Cre
Molecular description: The Wnt1 promoter preceded the cre recombinase coding sequence which was followed downstream by the Wnt1 enhancer. The Wnt1 regulatory sequences initially direct expression in the midbrain. After neural tube closure, expression occurs in the dorsal and ventral midlines of the midbrain and caudal diencephalon, the midbrain-hindbrain junction and in the dorsal spinal cord. Line 11 inserted into the gene at 6425500-6456783 (Build GRCm38/mm10) resulting in a 31,283 bp deletion. Founder line x has a copy number of greater than 5.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: H2az2Tg(Wnt1-cre)11Rth activity also observed in:
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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Fig. Wnt1 Brain P56
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Fig. Wnt1 Brain P7
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Fig. Wnt1 Embryo 1 E10.5
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Fig. Wnt1 Embryo 1 E15.5
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Fig. Wnt1 Embryo 2 E10.5
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Fig. Wnt1 Embryo 2 E15.5
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Fig. Wnt1 Embryo 3 E10.5
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Fig. Wnt1 Embryo 3 E15.5
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Fig. Wnt1 Embryo 4 E10.5
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Fig. Wnt1 Embryo 4 E15.5
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Fig. Wnt1 Eye P56
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Fig. Wnt1 Eye P7
J:193672 Fig. Wnt1 WM Embryo 1 E10.5 J:193672 Fig. Wnt1 WM Embryo 2 E10.5 J:193672 Fig. Wnt1 WM Embryo 4 E10.5 J:216865 Full Image
Fig. Wnt1 Adult Brain
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Fig. Wnt1 Adult Eye
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Fig. Wnt1 E10.5 Branchial Arches
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Fig. Wnt1 E10.5 Diencephalon
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Fig. Wnt1 E10.5 Head Mesenchyme
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Fig. Wnt1 E10.5 Hindbrain
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Fig. Wnt1 E10.5 Midbrain
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Fig. Wnt1 E10.5 Telencephalon
J:216865 Fig. Wnt1 E10.5 Whole Mount 1a
J:216865 Fig. Wnt1 E10.5 Whole Mount 1b J:216865 Fig. Wnt1 E10.5 Whole Mount 1c J:216865 Fig. Wnt1 E10.5 Whole Mount 1d J:216865 Fig. Wnt1 E10.5 Whole Mount 1e J:216865 Fig. Wnt1 E10.5 Whole Mount 1f J:216865 Fig. Wnt1 E10.5 Whole Mount 2a J:216865 Fig. Wnt1 E10.5 Whole Mount 2b J:216865 Fig. Wnt1 E10.5 Whole Mount 2c
J:216865 Fig. Wnt1 E10.5 Whole Mount 2d J:216865 Full Image
Fig. Wnt1 E15.5 Brain
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Fig. Wnt1 E15.5 Choroid Plexus
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Fig. Wnt1 E15.5 Cranium
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Fig. Wnt1 E15.5 Ear
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Fig. Wnt1 E15.5 Eye 1
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Fig. Wnt1 E15.5 Eye 2
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Fig. Wnt1 E15.5 Medulla Pons
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Fig. Wnt1 E15.5 Nose
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Fig. Wnt1 E15.5 Skin
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Fig. Wnt1 E15.5 Tongue
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 806 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory