5'CDR2 probe Probe Detail MGI Mouse MGI:9234

5'CDR2 probe Probe Detail

Name

5'CDR2 probe
Sequence Type

Not Specified
ID

MGI:9234
Region Covered

hybridizes to complementarity determining region 2 of the Igh-VJ558 H241/102 gene segment
Insert Size

23.0bp

Species

Not Specified

immunoglobulin heavy chain (J558 family)

J:15216 Gangemi RM, et al., J Immunol. 1993 Nov 1;151(9):4660-71

Notes: The band observed using SWR DNA (XbaI digest) is much less intense than bands originating from the other strains. The authors suggest diminished homology between probe and restriction fragment as a cause.

Endonuclease	Gene	Allele	Fragments	Strains
EcoRI	Igh-VJ558	a	5.8kb	BALB/c
		j	16.0kb	C3H, MRL, NZB
		p	5.3kb	DBA/2
XbaI	Igh-VJ558	c	6.0kb	DBA/2
		j	6.2kb	BALB/c, C3H, MRL, NZB, NZW
		p	5.7kb	SWR

J:15216 Gangemi RM, et al., Independently derived IgG anti-DNA autoantibodies from two lupus-prone mouse strains express a VH gene that is not present in most murine strains. J Immunol. 1993 Nov 1;151(9):4660-71

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24