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ptc probe Probe Detail
Nucleotide
Probe/Clone
  • Name
    ptc probe
  • Sequence Type
    Not Specified
  • ID
    MGI:3833867
  • Region Covered
    N-terminal coding region
  • Insert Site
    EcoRI
  • Insert Size
    0.9kb
Source
  • Species
    mouse, laboratory
Genes
Ptch1 patched 1
Expression
  • Assay Results
    164
References
J:31336 Goodrich LV, et al., Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev. 1996 Feb 1;10(3):301-12
J:52207 Chiang C, et al., Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev Biol. 1999 Jan 1;205(1):1-9
J:57297 St-Jacques B, et al., Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation [published erratum appears in Genes Dev 1999 Oct 1;13(19):2617]. Genes Dev. 1999 Aug 15;13(16):2072-86
J:101265 Kuijper S, et al., Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh. Dev Biol. 2005 Sep 15;285(2):533-44
J:104611 Moore-Scott BA, et al., Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs. Dev Biol. 2005 Feb 15;278(2):323-35
J:106405 Mackay DR, et al., The mouse Ovol2 gene is required for cranial neural tube development. Dev Biol. 2006 Mar 1;291(1):38-52
J:110617 Stottmann RW, et al., The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev Biol. 2006 Jul 15;295(2):647-63
J:114714 DeLaurier A, et al., Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb. Dev Biol. 2006 Nov 1;299(1):22-34
J:130163 Ratzka A, et al., Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development. Dev Dyn. 2008 Feb;237(2):339-53
J:150375 Cobourne MT, et al., Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol. 2009 Jul 1;331(1):38-49
J:154376 Stottmann RW, et al., Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain. Dev Biol. 2009 Nov 1;335(1):166-78
J:183829 Correa SM, et al., Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012 Apr;8(4):e1002569

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory