About   Help   FAQ
ZAP-L1210/R83-1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    ZAP-L1210/R83-1
  • Sequence Type
    cDNA
  • ID
    MGI:28439
  • Region Covered
    74bp 5' untranslated, entire 1764bp coding region, 449bp 3' untranslated, poly A tail
  • Vector Type
    Phage
  • Insert Site
    XhoI
  • Insert Size
    2.3kb
  • Note
    This clone is derived from a gene that produces alternate transcripts. Encodes splice variant I.
Source
  • Species
    mouse, laboratory
  • Tissue
    lymphocyte
  • Cell Line
    leukemia cell line L1210
Genes
Fpgs folylpolyglutamyl synthetase
Sequences
References
J:31712 Roy K, et al., Different antifolate-resistant L1210 cell variants with either increased or decreased folylpolyglutamate synthetase gene expression at the level of mRNA transcription. J Biol Chem. 1995 Nov 10;270(45):26918-22
J:35630 Roy K, et al., Organization and alternate splicing of the murine folylpolyglutamate synthetase gene. Different splice variants in L1210 cells encode mitochondrial or cytosolic forms of the enzyme. J Biol Chem. 1996 Sep 27;271(39):23820-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/09/2025
MGI 6.24
The Jackson Laboratory