ZAP-L1210/R83-1
Probe Detail
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Name
ZAP-L1210/R83-1
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Sequence Type
cDNA
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ID
MGI:28439
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Region Covered
74bp 5' untranslated, entire 1764bp coding region, 449bp 3' untranslated, poly A tail
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Vector Type
Phage
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Insert Site
XhoI
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Insert Size
2.3kb
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Note
This clone is derived from a gene that produces alternate transcripts. Encodes splice variant I.
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Species
mouse, laboratory
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Tissue
lymphocyte
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Cell Line
leukemia cell line L1210
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Fpgs
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folylpolyglutamyl synthetase
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J:31712
Roy K, et al., Different antifolate-resistant L1210 cell variants with either increased or decreased folylpolyglutamate synthetase gene expression at the level of mRNA transcription. J Biol Chem. 1995 Nov 10;270(45):26918-22
J:35630
Roy K, et al., Organization and alternate splicing of the murine folylpolyglutamate synthetase gene. Different splice variants in L1210 cells encode mitochondrial or cytosolic forms of the enzyme. J Biol Chem. 1996 Sep 27;271(39):23820-7