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86T5 Probe Detail
Nucleotide
Probe/Clone
  • Name
    86T5
  • Sequence Type
    cDNA
  • ID
    MGI:15054
  • Region Covered
    encodes D, J[b]1.3 and C[b]1 gene segments
  • Child Clone
    C-beta
  • Vector Type
    Phage
  • Insert Site
    EcoRI
  • Insert Size
    ~.6 kb
  • Note
    Probe insert was subcloned into pUC9 and also hybridizes to C[b]1 and C[b]2.
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Tissue
    thymocyte
Genes
Tcrb-C T cell receptor beta, constant region
Tcrb-D T cell receptor beta, D region
Tcrb-J T cell receptor beta, joining region
Sequences
K01082 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
X00440 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:7825 Epstein R, et al., J Exp Med. 1985 May 1;161(5):1219-24
Endonuclease Gene Allele Fragments Strains
EcoRI Tcrb-D a 7.8,3.1kb SJL/J
c 9.4,2.0kb B10.A-H2a, BALB/c, C57L
References
J:7354 Hedrick SM, et al., Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins. Nature. 1984 Mar 8-14;308(5955):153-8
J:7557 Lee NE, et al., Murine T cell receptor beta chain is encoded on chromosome 6. J Exp Med. 1984 Sep 1;160(3):905-13
J:7825 Epstein R, et al., Genetic markers of the antigen-specific T cell receptor locus. J Exp Med. 1985 May 1;161(5):1219-24
J:20304 Vasmel WL, et al., Refinement and precision in the classification of murine lymphomas by genotyping with immunoglobulin and T cell receptor probes. Leukemia. 1987 Mar;1(3):155-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory