About   Help   FAQ
p597.1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    p597.1
  • Sequence Type
    genomic
  • ID
    MGI:13249
  • Region Covered
    unique cellular sequence flanking the proviral insertion site
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    500bp
  • Synonyms
    probe B
Source
  • Species
    mouse, laboratory
  • Strain
    BXH2/TyJ
  • Tissue
    myeloid tumor
Genes
Evi2a ecotropic viral integration site 2a
Sequences
M34896 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
M34897 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:9562 Buchberg AM, et al., Oncogene Res. 1988;2(2):149-65
Endonuclease Gene Allele Fragments Strains
BamHI Evi2a a not given AKR/J
b not given A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
EcoRI Evi2a a not given AKR/J
b not given A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
EcoRV Evi2a a not given AKR/J
b not given A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
HindIII Evi2a a 1.9kb AKR/J
b 2.3kb A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
MspI Evi2a a 6.7kb AKR/J
b 6.8kb A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
TaqI Evi2a a 4.4kb AKR/J
b 2.0kb A/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J
s 1.7kb M. spretus
J:9831 Buchberg AM, et al., Genetics. 1989 May;122(1):153-61
Endonuclease Gene Allele Fragments Strains
TaqI Evi2a b 2.1kb C57BL/6J
s 1.7kb M. spretus
J:1905 Takahashi Y, et al., J Exp Med. 1992 Mar 1;175(3):873-6
Endonuclease Gene Allele Fragments Strains
StuI Evi2a a 4.9kb AKR/Ms, BALB/c
b 5.4kb C57BL/6N
J:20027 Mock BA, et al., Eur J Immunogenet. 1994 Aug;21(4):231-8
Notes: A 500bp SalI/EcoRI fragment of p597.1 was used as a hybridization probe on Southern blots.
Endonuclease Gene Allele Fragments Strains
HindIII Evi2a c 4.3,1.8kb BALB/cAnPt
s 4.3,2.3kb M. spretus
J:22862 Kozak CA, et al., Mamm Genome. 1995 Feb;6(2):142-4
Endonuclease Gene Allele Fragments Strains
BamHI Evi2a n not given C58/J, NFS/N
s not given M. spretus
EcoRI Evi2a m not given M. m. musculus
n not given C58/J, NFS/N
J:24223 Blackburn CC, et al., Genomics. 1995 Mar 20;26(2):308-17
Endonuclease Gene Allele Fragments Strains
StuI Evi2a a 5.4kb A.SW-H2s/Sn, C.Foxn1nu, CBA.NU, CBA/CaH, NZC, NZC.NU, NZW, NZW.NU
c 4.9kb BALB/cAn
References
J:9562 Buchberg AM, et al., Localization of Evi-2 to chromosome 11: linkage to other proto-oncogene and growth factor loci using interspecific backcross mice. Oncogene Res. 1988;2(2):149-65
J:9831 Buchberg AM, et al., A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human. Genetics. 1989 May;122(1):153-61
J:10694 Buchberg AM, et al., Evi-2, a common integration site involved in murine myeloid leukemogenesis. Mol Cell Biol. 1990 Sep;10(9):4658-66
J:1905 Takahashi Y, et al., Mapping of the nu gene using congenic nude strains and in situ hybridization. J Exp Med. 1992 Mar 1;175(3):873-6
J:20027 Mock BA, et al., The inducible form of nitric oxide synthase (NOS2) isolated from murine macrophages maps near the nude mutation on mouse chromosome 11. Eur J Immunogenet. 1994 Aug;21(4):231-8
J:22862 Kozak CA, et al., Localization of three genes expressed in retina on mouse chromosome 11. Mamm Genome. 1995 Feb;6(2):142-4
J:24223 Blackburn CC, et al., A high-resolution map of the chromosomal region surrounding the nude gene. Genomics. 1995 Mar 20;26(2):308-17
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory